Split-eyebrow vehicle-controlled trial

GHK-STUDY-P021

Bo et al. (2026), randomized double-blind split-eyebrow study.

Study design

Record details

Design: Randomized, double-blind, split-eyebrow, vehicle-controlled study over 12 weeks.
Population or model: 18 adults.
Material tested: Serum containing a supplied 2% copper peptide (GHK-Cu) ingredient.
Comparator: Identical vehicle applied to the contralateral eyebrow.

Evidence record

Endpoints, findings, and limitations

Endpoints

Instrumental eyebrow hair count.

Qualified findings

The active side showed about 1.6 additional hairs, with a between-side result of p=0.049.

Limitations

Small sample, short duration, borderline statistical result, and no independent replication. The study concerns eyebrows and does not establish scalp-hair or alopecia efficacy.

Reports and sources

Reference ledger

GHK-P021Primary paper

The efficacy of 2% copper peptide (GHK-Cu) serum for eyebrow hypotrichosis: a randomized, double-blind, vehicle-controlled study

Bo SL et al.. Procedia of Multidisciplinary Research(2026)
Journal record and thesis full text. Thesis: https://mfuir.mfu.ac.th/xmlui/bitstream/handle/123456789/1706/141538-Fulltext.pdf?sequence=1